Cancer: Experiments and Concepts by R. Süss, V. Kinzel, J. D. Scribner (auth.) PDF

By R. Süss, V. Kinzel, J. D. Scribner (auth.)

ISBN-10: 038790042X

ISBN-13: 9780387900421

ISBN-10: 1461298415

ISBN-13: 9781461298410

This e-book quite needs to be learn on holiday, only for leisure. Granted, melanoma is, actually, a dangerous critical subject, and melanoma learn is basically part of medication with Hippocrates in its again­ flooring. but, melanoma learn is usually traditional technology, and as such it yields the thrill and sorrows of any technology. The melanoma challenge can be a mind teaser, a problem for the curious. This introductory document on experimental melanoma learn is there­ fore directed to curious scholars of many disciplines: certainly to scientific scholars, but in addition to chemists and physicists who've an curiosity in organic phenomena; biology scholars would certainly en­ counter pr9blems ordinary to their box in what's supposedly a medi­ cal one. we've tried to jot down with no assumptions to a definite measure, for a chemist is largely in over his head in medication, and a doctor has simply the slightest suggestion of the chemical difficulties im­ portant in melanoma study. We had no purpose of giving an entire view of the sphere, and from the massive variety of diverse strains of improvement we've selected just a couple of. Chemotherapy, as an ex­ plentiful, has been taken care of fairly cursorily, in addition to RNA tumor viruses, even though it is feasible that simply those topics are in particular very important for human tumors. Tumor induction through radiation might in basic terms be pointed out in passing, even with its nice useful importance; equally the function of hormones was once purely intimated.

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Extra resources for Cancer: Experiments and Concepts

Sample text

Even the biology of our time and scientific medicine are more and more to be considered as exact science. The fascination with the phenomenon of living things is still an important driving force of biological research, but vis vitalis and vis regenerativa have been bid farewell, with regrets and relief simultaneously. Simple DNA molecules have won the race, and the rational language of cybernetics today dominates such basic biological phenomena as inheritance and adaptation. Cancer research, to be sure, remained in large degree a "systematic art," and we have not yet been as successful in building a generally valid and generally accepted structure of ideas.

An attempt was then made to approach N-OH-MAB by the back door: although (III) could not be synthesized, its ester could be prepared in one step from MAB. 31 This ester was imagined to be very easily hydrolyzed, and could conceivably yield "transient" free N-OH-MAB. Relatively large quantities were prepared and the testing for carcinogenicity begun. At this point let us put off discussing the biological results and instead consider another project going on in the Miller group at that time, a project which seemed to have nothing to do with N-hydroxylation.

This painting is repeated twice a week until the first papillomas (warts) are visible and can be counted. The following table outlines such an experiment with two different organic compounds: (Table 2).

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Cancer: Experiments and Concepts by R. Süss, V. Kinzel, J. D. Scribner (auth.)


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